The impact of microRNA-mediated PI3K/AKT signaling on epithelial-mesenchymal transition and cancer stemness in endometrial cancer

Activation of the PI3K/AKT pathway, a common mechanism in all subtypes of endometrial cancers (endometrioid and non-endometrioid tumors), has important roles in contributing to epithelial-mesenchymal transition (EMT) and cancer stem cell (CSC) features. MicroRNAs (miRNAs) are small non-coding RNA mo...

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Autores principales: Dong, Peixin, Konno, Yosuke, Watari, Hidemichi, Hosaka, Masayoshi, Noguchi, Masayuki, Sakuragi, Noriaki
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145234/
https://ncbi.nlm.nih.gov/pubmed/25141911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0231-0
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