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Identification of novel epitopes from human papillomavirus type 18 E7 that can sensitize PBMCs of multiple HLA class I against human cervical cancer

BACKGROUND: To identify the novel epitopes from the human papillomavirus type 18 E7 which can sensitize PBMCs of four different major HLA class I A allele. METHODS: Twenty-four synthetic overlapping 15-amino acid peptides were screened by measuring the frequency of CD8(+) cytotoxic T lymphocytes (CT...

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Detalhes bibliográficos
Main Authors: Kim, Sunghoon, Chung, Hye Won, Lee, Kyoung-Ryul, Lim, Jong-Baeck
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145224/
https://ncbi.nlm.nih.gov/pubmed/25141788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0229-7
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