Significant clinical response to JAK1/2 inhibition in a patient with CSF3R-T618I-positive atypical chronic myeloid leukemia

Mutations in CSF3R (colony-stimulating factor 3 receptor) are frequent oncogenic drivers in chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML). Here we describe a 75 year old man who was diagnosed with CSF3R-T618I-positive atypical CML. He presented with leukocytosis, a...

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Detalles Bibliográficos
Main Authors: Dao, Kim-Hien T., Solti, Magdolna B., Maxson, Julia E., Winton, Elliott F., Press, Richard D., Druker, Brian J., Tyner, Jeffrey W.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2014
Assuntos:
Case Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145163/
https://ncbi.nlm.nih.gov/pubmed/25180155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lrr.2014.07.002
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