Epigenetic Variation in the Mu-opioid Receptor Gene in Infants with Neonatal Abstinence Syndrome

OBJECTIVE: Neonatal abstinence syndrome (NAS) from in utero opioid exposure is highly variable with genetic factors appearing to play an important role. Epigenetic changes in cytosine:guanine (CpG) dinucleotide methylation can occur after drug exposure and may help to explain NAS variability. We cor...

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Autores principales: Wachman, Elisha M, Hayes, Marie J, Lester, Barry M, Terrin, Norma, Brown, Mark S, Nielsen, David A, Davis, Jonathan M
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145036/
https://ncbi.nlm.nih.gov/pubmed/24996986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpeds.2014.05.040
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