Association of maternal and infant variants in PNOC and COMT genes with Neonatal Abstinence Syndrome severity

BACKGROUND AND OBJECTIVES: There is significant variability in severity of neonatal abstinence syndrome (NAS) due to in-utero opioid exposure. Our previous study identified single nucleotide polymorphisms (SNPs) in the prepronociceptin (PNOC) and catechol-O-methyltransferase (COMT) genes that were a...

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Detalhes bibliográficos
Publicado no:Am J Addict
Main Authors: Wachman, Elisha M, Hayes, Marie J, Sherva, Richard, Brown, Mark S, Shrestha, Hira, Logan, Beth A, Heller, Nicole A, Nielsen, David A, Farrer, Lindsay A
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206487/
https://ncbi.nlm.nih.gov/pubmed/27983768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajad.12483
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