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Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development

SIP1 encodes a DNA-binding transcription factor that regulates multiple developmental processes, as highlighted by the pleiotropic defects observed in Mowat-Wilson Syndrome, which results from mutations in this gene. Further, in adults, dysregulated SIP1 expression has been implicated in both cancer...

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Detalhes bibliográficos
Main Authors: Manthey, Abby L., Lachke, Salil A., FitzGerald, Paul G., Mason, Robert W., Scheiblin, David A., McDonald, John H., Duncan, Melinda K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144920/
https://ncbi.nlm.nih.gov/pubmed/24161570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2013.09.005
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