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Do Mantle Cell Lymphomas have an “Achilles Heel”?

PURPOSE OF REVIEW: Mantle cell lymphoma (MCL) is a mature B-cell malignancy that continues to have a high mortality rate. In this manuscript we discuss key pathogenic pathways in MCL biology and their possible therapeutic targeting. RECENT FINDINGS: In addition to Cyclin-D1 the transcription factor...

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Autori principali: Saba, Nakhle, Wiestner, Adrian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144918/
https://ncbi.nlm.nih.gov/pubmed/24857884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000057
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