Expression Levels of pvcrt-o and pvmdr-1 Are Associated with Chloroquine Resistance and Severe Plasmodium vivax Malaria in Patients of the Brazilian Amazon

Molecular markers associated with the increase of chloroquine resistance and disease severity in Plasmodium vivax are needed. The objective of this study was to evaluate the expression levels of pvcrt-o and pvmdr-1 genes in a group of patients presenting CQRPv and patients who developed severe compl...

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Autori principali: Melo, Gisely C., Monteiro, Wuelton M., Siqueira, André M., Silva, Siuhelem R., Magalhães, Belisa M. L., Alencar, Aline C. C., Kuehn, Andrea, Portillo, Hernando A. del., Fernandez-Becerra, Carmen, Lacerda, Marcus V. G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144906/
https://ncbi.nlm.nih.gov/pubmed/25157811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105922
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