Activation of α-7 Nicotinic Acetylcholine Receptor Reduces Ischemic Stroke Injury through Reduction of Pro-Inflammatory Macrophages and Oxidative Stress

Activation of α-7 nicotinic acetylcholine receptor (α-7 nAchR) has a neuro-protective effect on ischemic and hemorrhagic stroke. However, the underlying mechanism is not completely understood. We hypothesized that α-7 nAchR agonist protects brain injury after ischemic stroke through reduction of pro...

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Bibliographic Details
Main Authors: Han, Zhenying, Shen, Fanxia, He, Yue, Degos, Vincent, Camus, Marine, Maze, Mervyn, Young, William L., Su, Hua
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144901/
https://ncbi.nlm.nih.gov/pubmed/25157794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105711
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