Tumour Microenvironments Induce Expression of Urokinase Plasminogen Activator Receptor (uPAR) and Concomitant Activation of Gelatinolytic Enzymes

BACKGROUND: The urokinase plasminogen activator receptor (uPAR) is associated with poor prognosis in oral squamous cell carcinoma (OSCC), and increased expression of uPAR is often found at the invasive tumour front. The aim of the current study was to elucidate the role of uPAR in invasion and metas...

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Detalhes bibliográficos
Main Authors: Magnussen, Synnøve, Hadler-Olsen, Elin, Latysheva, Nadezhda, Pirila, Emma, Steigen, Sonja E., Hanes, Robert, Salo, Tuula, Winberg, Jan-Olof, Uhlin-Hansen, Lars, Svineng, Gunbjørg
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144900/
https://ncbi.nlm.nih.gov/pubmed/25157856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105929
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