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Gametocytocidal Screen Identifies Novel Chemical Classes with Plasmodium falciparum Transmission Blocking Activity

Discovery of transmission blocking compounds is an important intervention strategy necessary to eliminate and eradicate malaria. To date only a small number of drugs that inhibit gametocyte development and thereby transmission from the mosquito to the human host exist. This limitation is largely due...

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Autori principali: Sanders, Natalie G., Sullivan, David J., Mlambo, Godfree, Dimopoulos, George, Tripathi, Abhai K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144897/
https://ncbi.nlm.nih.gov/pubmed/25157792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105817
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