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Enzymatic Oxidation of Cholesterol: Properties and Functional Effects of Cholestenone in Cell Membranes

Bacterial cholesterol oxidase is commonly used as an experimental tool to reduce cellular cholesterol content. That the treatment also generates the poorly degradable metabolite 4-cholesten-3-one (cholestenone) has received less attention. Here, we investigated the membrane partitioning of cholesten...

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Hlavní autoři: Neuvonen, Maarit, Manna, Moutusi, Mokkila, Sini, Javanainen, Matti, Rog, Tomasz, Liu, Zheng, Bittman, Robert, Vattulainen, Ilpo, Ikonen, Elina
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144813/
https://ncbi.nlm.nih.gov/pubmed/25157633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103743
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