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[6]-Gingerol Induces Caspase-Dependent Apoptosis and Prevents PMA-Induced Proliferation in Colon Cancer Cells by Inhibiting MAPK/AP-1 Signaling

We report mechanism-based evidence for the anticancer and chemopreventive efficacy of [6]-gingerol, the major active principle of the medicinal plant, Ginger (Zingiber officinale), in colon cancer cells. The compound was evaluated in two human colon cancer cell lines for its cytotoxic effect and the...

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Bibliografiske detaljer
Main Authors: Radhakrishnan, EK, Bava, Smitha V., Narayanan, Sai Shyam, Nath, Lekshmi R., Thulasidasan, Arun Kumar T., Soniya, Eppurathu Vasudevan, Anto, Ruby John
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144808/
https://ncbi.nlm.nih.gov/pubmed/25157570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104401
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