Nicotine-induced survival signaling in lung cancer cells is dependent on their p53 status while its down-regulation by curcumin is independent

BACKGROUND: Lung cancer is the most lethal cancer and almost 90% of lung cancer is due to cigarette smoking. Even though nicotine, one of the major ingredients of cigarette smoke and the causative agent for addiction, is not a carcinogen by itself, several investigators have shown that nicotine can...

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Detalhes bibliográficos
Main Authors: Puliyappadamba, Vineshkumar T, Cheriyan, Vino T, Thulasidasan, Arun Kumar T, Bava, Smitha V, Vinod, Balachandran S, Prabhu, Priya R, Varghese, Ranji, Bevin, Arathy, Venugopal, Shalini, Anto, Ruby John
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936340/
https://ncbi.nlm.nih.gov/pubmed/20727180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-220
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