Responses against a Subdominant CD8(+) T Cell Epitope Protect against Immunopathology Caused by a Dominant Epitope

CD8(+) T cell responses are critical for the control of virus infections. Following infection, epitope-specific responses establish an unpredictable but reproducible pattern of dominance that is dictated by a large number of both positive and negative factors. Immunodomination, or diminution of subd...

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Bibliographic Details
Main Authors: Ruckwardt, Tracy J., Luongo, Cindy, Malloy, Allison M. W., Liu, Jie, Chen, Man, Collins, Peter L., Graham, Barney S.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144756/
https://ncbi.nlm.nih.gov/pubmed/20833834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001606
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