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A BTLA-mediated bait-and-switch strategy permits Listeria expansion in CD8α(+) DCs to promote long term T cell responses

Listeria monocytogenes infected CD8α(+) DCs in the spleen are essential for CD8(+) T cell generation. CD8α(+) DCs are also necessary for Listeria expansion and dissemination within the host. The mechanisms that regulate CD8α(+) DCs to allow Listeria expansion are unclear. We find that activating the...

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Detalhes bibliográficos
Main Authors: Yang, Xuanming, Zhang, Xunmin, Sun, Yonglian, Tu, Tony, Fu, May Lynne, Miller, Mendy, Fu, Yang-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144681/
https://ncbi.nlm.nih.gov/pubmed/25011109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.05.021
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