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A BTLA-mediated bait-and-switch strategy permits Listeria expansion in CD8α(+) DCs to promote long term T cell responses
Listeria monocytogenes infected CD8α(+) DCs in the spleen are essential for CD8(+) T cell generation. CD8α(+) DCs are also necessary for Listeria expansion and dissemination within the host. The mechanisms that regulate CD8α(+) DCs to allow Listeria expansion are unclear. We find that activating the...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144681/ https://ncbi.nlm.nih.gov/pubmed/25011109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.05.021 |
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