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Targeting the tumor microenvironment with interferon-β bridges innate and adaptive immune responses
Antibodies (Abs) that preferentially target oncogenic receptors have been increasingly used for cancer therapy, but tumors often acquire intrinsic Ab-resistance after prolonged and costly treatment. Here, we arm the Ab with IFNβ and observed that it is more potent than first generation of Ab for con...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3927846/ https://ncbi.nlm.nih.gov/pubmed/24434209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2013.12.004 |
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