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Cetuximab-mediated Tumor Regression Depends on Innate and Adaptive Immune Responses
Epidermal growth factor receptor (EGFR) over-signaling leads to more aggressive tumor growth. The antitumor effect of Cetuximab, an anti-EGFR antibody, depends on oncogenic-signal blockade leading to tumor cell apoptosis and antibody dependent cell-mediated cytotoxicity (ADCC). However, whether adap...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538305/ https://ncbi.nlm.nih.gov/pubmed/22990672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.184 |
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