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DIFFERENT MECHANISMS OF TUMOR GROWTH INHIBITION BY BLOCKADE OF IGF-IR IN U87-INDUCED AND STEM-LIKE CELL-INDUCED GLIOBLASTOMAS
BACKGROUND: Insulin-like growth factor receptor I (IGF-IR) signaling can contribute to the formation, maintenance, and/or progression of many diverse tumor types, including glioblastomas. We investigated the effect of an IGF-IR blocking antibody (IMC-A12) on tumors derived either from U87 cells or f...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144601/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.53 |
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