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RB1 SUPPRESSION IS RESPONSIBLE FOR ACQUIRED CDK4/6 INHIBITOR RESISTANCE IN GLIOBLASTOMA

BACKGROUND: The observation of glioblastoma (GBM) tumors acquiring resistance to treatment is a well-established clinical reality. Increased understanding of GBM adaptive mechanisms to specific therapies is important for achieving improved treatment, and treatment outcomes for GBM patients, by targe...

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Detalhes bibliográficos
Main Authors: James, C. David, Lu, Yu-Jen, Ozawa, Tomoko, Prados, Michael D., Waldman, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144588/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.41
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