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AN ALL HUMAN 3D IN VITRO MODEL OF THE BLOOD BRAIN BARRIER IN NANOPARTICLE DELIVERY AND CANCER METASTASIS STUDIES
BACKGROUND: The blood-brain barrier (B-BB) is a dynamic functional unit consisting of endothelial cells, astrocytic endfeet and pericytes embedded in a specialized basement membrane. Most in vitro studies examine the ability of therapeutics to cross the B-BB using monolayer cultures or mixed species...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144585/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.39 |
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