AN ALL HUMAN 3D IN VITRO MODEL OF THE BLOOD BRAIN BARRIER IN NANOPARTICLE DELIVERY AND CANCER METASTASIS STUDIES

BACKGROUND: The blood-brain barrier (B-BB) is a dynamic functional unit consisting of endothelial cells, astrocytic endfeet and pericytes embedded in a specialized basement membrane. Most in vitro studies examine the ability of therapeutics to cross the B-BB using monolayer cultures or mixed species...

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Main Authors: Pilkington, Geoffrey John, Maherally, Zaynah, Jassam, Samah, Barbu, Eugen, Fillmore, Helen
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2014
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144585/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.39
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