DETAILED MOLECULAR CHARACTERISATION OF DIFFUSE INTRINSIC PONTINE GLIOMAS IDENTIFIES THREE MOLECULAR SUBGROUPS AND A NOVEL CANCER DRIVER, ACVR1

BACKGROUND: Diffuse intrinsic pontine glioma (DIPG) is a devastating pediatric brain tumor with no effective therapy and near 100% fatality. The failure of most therapies can be attributed to the delicate location of these tumors and choosing therapies based on assumptions that DIPGs are molecularly...

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Auteurs principaux: Hawkins, Cynthia, Buczkowicz, Pawel, Hoeman, Christine, Rakopoulos, Patricia, Pajovic, Sanja, Morrison, Andrew, Jones, Chris, Bouffet, Eric, Bartels, Ute, Becher, Oren
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
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abstracts
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144558/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.14
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