EPIGENOME ALTERATIONS DEFINE LETHAL CIMP POSITIVE EPENDYMOMAS OF INFANCY

BACKGROUND: Ependymomas are common childhood brain tumors that occur throughout the nervous system, but are most common in the pediatric hindbrain. Current standard therapy comprises surgery and radiation, but not cytotoxic chemotherapy as it does not further increase survival. METHODS: We undertook...

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Hauptverfasser: Taylor, MIchael D., Mack, Steve, Witt, Hendrik, Dirks, Peter, Pfister, Stefan, Korshunov, Andrey
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144526/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.58
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