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EPIGENOME ALTERATIONS DEFINE LETHAL CIMP POSITIVE EPENDYMOMAS OF INFANCY

BACKGROUND: Ependymomas are common childhood brain tumors that occur throughout the nervous system, but are most common in the pediatric hindbrain. Current standard therapy comprises surgery and radiation, but not cytotoxic chemotherapy as it does not further increase survival. METHODS: We undertook...

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Detalhes bibliográficos
Main Authors: Taylor, MIchael D., Mack, Steve, Witt, Hendrik, Dirks, Peter, Pfister, Stefan, Korshunov, Andrey
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144526/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.58
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