EPIGENETIC REGULATION OF GBM CELL STEMNESS AND TUMOR PROPAGATING CAPACITY BY OCT4 AND SOX2

BACKGROUND: (blind field). METHODS: Experiments utilized human glioblastoma neurosphere lines and low passage (<5) primary neurospheres derived from clinical GBM specimens enriched in GBM sphere-forming stem cells. The Adherent GBM cell lines that lack stem-like tumor-propagating cells were used...

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Hauptverfasser: Laterra, John, Lopez-Bertoni, Hernando, Lal, Bachchu, Li, Angela, Caplan, Michael, Guerrero-Cázares, Hugo, Eberhart, Charles G., Quiñones-Hinojosa, Alfredo, Li, Yunqing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144522/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.54
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