INCREASED PERFUSION DUE TO VASCULAR NORMALIZATION IMPROVES OXYGENATION AND SURVIVAL IN GLIOBLASTOMA PATIENTS TREATED WITH CEDIRANIB WITH OR WITHOUT CHEMORADIATION

BACKGROUND: (blind field). METHODS: We evaluated MRI markers in 84 GBM patients enrolled in phase 2 trials (NCT00305656, NCT00662506) to investigate the mechanisms of tumor response to anti-VEGF treatment. Forty newly diagnosed GBM (nGBM) patients were treated with the oral pan-VEGFR inhibitor, cedi...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Batchelor, Tracy T., Gerstner, Elizabeth R., Emblem, Kyrre E., Duda, Dan G., Kalpathy-Cramer, Jayashree, Snuderl, Matija, Ancukiewicz, Marek, Polaskova, Pavlina, Pinho, Marco C., Jennings, Dominique, Plotkin, Scott R., Chi, Andrew S., Eichler, April F., Dietrich, Jorg, Hochberg, Fred H., Lu-Emerson, Christine, Iafrate, A. John, Ivy, S. Percy, Rosen, Bruce, Loeffler, Jay S., Wen, Patrick Y., Sorensen, A. Greg, Jain, Rakesh K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
Soggetti:
abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144509/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.42
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi