Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation

Antiangiogenic therapy has shown clear activity and improved survival benefit for certain tumor types. However, an incomplete understanding of the mechanisms of action of antiangiogenic agents has hindered optimization and broader application of this new therapeutic modality. In particular, the impa...

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Autori principali: Batchelor, Tracy T., Gerstner, Elizabeth R., Emblem, Kyrre E., Duda, Dan G., Kalpathy-Cramer, Jayashree, Snuderl, Matija, Ancukiewicz, Marek, Polaskova, Pavlina, Pinho, Marco C., Jennings, Dominique, Plotkin, Scott R., Chi, Andrew S., Eichler, April F., Dietrich, Jorg, Hochberg, Fred H., Lu-Emerson, Christine, Iafrate, A. John, Ivy, S. Percy, Rosen, Bruce R., Loeffler, Jay S., Wen, Patrick Y., Sorensen, A. Greg, Jain, Rakesh K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839699/
https://ncbi.nlm.nih.gov/pubmed/24190997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318022110
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