GENETIC AND EPIGENETIC DEREGULATION ARE ASSOCIATED WITH THE ABERRANT EXPRESSION OF A STEM CELL RELATED HOX GENE SIGNATURE IN GLIOBLASTOMA

BACKGROUND: (blind field). METHODS: Multidimensional molecular profiles of 70 gliobalstoma and 4 non-tumoral brain samples were obtained, comprising gene expression, DNA methylation, and gene copy number alterations. Validation datasets were downloaded from the public domain including The Cancer Gen...

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Autori principali: Hegi, Monika E., Kurscheid, Sebastiann, Sciuscio, Davide, Samarzija, Ivana, Stupp, Roger, Delorenzi, Mauro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144491/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.26
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