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Aerosol Interleukin-2 Induces Natural Killer Cell Proliferation in the Lung and Combination Therapy Improves the Survival of Mice with Osteosarcoma Lung Metastasis

BACKGROUND: We have previously shown that aerosol interleukin-2 [IL-2] increased the number of intravenously injected human natural killer [NK] cells in the lungs. In this study we investigated whether this increase was secondary to NK cell proliferation and determined the site of the proliferation....

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Detalles Bibliográficos
Main Authors: Guma, Sergei R., Lee, Dean A., Yu, Ling, Gordon, Nancy, Kleinerman, Eugenie S.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144337/
https://ncbi.nlm.nih.gov/pubmed/24610870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.25019
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