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Mutations in BALB Mitochondrial DNA Induce CCL20 Up-regulation Promoting Tumorigenic Phenotypes
mtDNA mutations are common in human cancers and are thought to contribute to the process of neoplasia. We examined the role of mtDNA mutations in skin cancer by generating fibroblast cybrids harboring a mutation in the gene encoding the mitochondrial tRNA for arginine. This somatic mutation (9821ins...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144272/ https://ncbi.nlm.nih.gov/pubmed/25177208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2014.07.003 |
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