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Identifying rare-variant associations in parent-child trios using a Gaussian support vector machine

As the availability of cost-effective high-throughput sequencing technology increases, genetic research is beginning to focus on identifying the contributions of rare variants (RVs) to complex traits. Using RVs to detect associated genes requires statistical approaches that mitigate the lack of powe...

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Detalhes bibliográficos
Main Authors: Lu, Ake T, Cantor, Rita M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143758/
https://ncbi.nlm.nih.gov/pubmed/25519420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S98
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