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Identifying rare-variant associations in parent-child trios using a Gaussian support vector machine

As the availability of cost-effective high-throughput sequencing technology increases, genetic research is beginning to focus on identifying the contributions of rare variants (RVs) to complex traits. Using RVs to detect associated genes requires statistical approaches that mitigate the lack of powe...

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Hlavní autoři: Lu, Ake T, Cantor, Rita M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143758/
https://ncbi.nlm.nih.gov/pubmed/25519420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S98
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