An exploration of heterogeneity in genetic analysis of complex pedigrees: linkage and association using whole genome sequencing data in the MAP4 region

We conduct pedigree-based linkage and association analyses of simulated systolic blood pressure data in the nonascertained large Mexican American pedigrees provided by Genetic Analysis Workshop 18, focusing on observed sequence variants in MAP4 on chromosome 3. Because pedigrees are large and sequen...

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Bibliographic Details
Main Authors: Bull, Shelley B, Chen, Zhijian, Tan, Kuan-Rui, Poirier, Julia
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Proceedings
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143705/
https://ncbi.nlm.nih.gov/pubmed/25519361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S107
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