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Accounting for relatedness in family-based association studies: application to Genetic Analysis Workshop 18 data

In the last few years, a bewildering variety of methods/software packages that use linear mixed models to account for sample relatedness on the basis of genome-wide genomic information have been proposed. We compared these approaches as implemented in the programs EMMAX, FaST-LMM, Gemma, and GenABEL...

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Detalhes bibliográficos
Main Authors: Eu-ahsunthornwattana, Jakris, Howey, Richard AJ, Cordell, Heather J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143672/
https://ncbi.nlm.nih.gov/pubmed/25519407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S79
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