Comparison of Methods to Account for Relatedness in Genome-Wide Association Studies with Family-Based Data

Approaches based on linear mixed models (LMMs) have recently gained popularity for modelling population substructure and relatedness in genome-wide association studies. In the last few years, a bewildering variety of different LMM methods/software packages have been developed, but it is not always c...

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Bibliographic Details
Main Authors: Eu-ahsunthornwattana, Jakris, Miller, E. Nancy, Fakiola, Michaela, Jeronimo, Selma M. B., Blackwell, Jenefer M., Cordell, Heather J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102448/
https://ncbi.nlm.nih.gov/pubmed/25033443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004445
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