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RNA sequencing: from tag-based profiling to resolving complete transcript structure

Technological advances in the sequencing field support in-depth characterization of the transcriptome. Here, we review genome-wide RNA sequencing methods used to investigate specific aspects of gene expression and its regulation, from transcription to RNA processing and translation. We discuss tag-b...

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Autori principali: de Klerk, Eleonora, den Dunnen, Johan T., ‘t Hoen, Peter A. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Basel 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143603/
https://ncbi.nlm.nih.gov/pubmed/24827995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-014-1637-9
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