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Increased sensitivity of next generation sequencing-based expression profiling after globin reduction in human blood RNA

BACKGROUND: Transcriptome analysis is of great interest in clinical research, where significant differences between individuals can be translated into biomarkers of disease. Although next generation sequencing provides robust, comparable and highly informative expression profiling data, with several...

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Detalhes bibliográficos
Main Authors: Mastrokolias, Anastasios, den Dunnen, Johan T, van Ommen, GertJan B, 't Hoen, Peter AC, van Roon-Mom, Willeke MC
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275489/
https://ncbi.nlm.nih.gov/pubmed/22257641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-28
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