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Increased sensitivity of next generation sequencing-based expression profiling after globin reduction in human blood RNA

BACKGROUND: Transcriptome analysis is of great interest in clinical research, where significant differences between individuals can be translated into biomarkers of disease. Although next generation sequencing provides robust, comparable and highly informative expression profiling data, with several...

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Bibliografiska uppgifter
Huvudupphovsmän: Mastrokolias, Anastasios, den Dunnen, Johan T, van Ommen, GertJan B, 't Hoen, Peter AC, van Roon-Mom, Willeke MC
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275489/
https://ncbi.nlm.nih.gov/pubmed/22257641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-28
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