Computational analyses of curcuminoid analogs against kinase domain of HER2

BACKGROUND: Human epidermal growth factor receptor 2 (HER2) has an important role in cancer aggressiveness and poor prognosis. HER2 has been used as a drug target for cancers. In particular, to effectively treat HER2-positive cancer, small molecule inhibitors were developed to target HER2 kinase. Kn...

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Bibliographic Details
Main Authors: Yim-im, Wannarat, Sawatdichaikul, Orathai, Semsri, Suwanna, Horata, Natharinee, Mokmak, Wanwimon, Tongsima, Sissades, Suksamrarn, Apichart, Choowongkomon, Kiattawee
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143557/
https://ncbi.nlm.nih.gov/pubmed/25089037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-261
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