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A Cooperative N-Heterocyclic Carbene-Chiral Phosphate Catalysis System for Allenolate Annulations
[Image: see text] The first highly enantioselective NHC-catalyzed [3+2] annulation reaction with α,β-alkynals and α-ketoesters has been developed. A new mode of cooperative catalysis involving the combination of a chiral Brønsted acid and a C(1)-symmetric biaryl saturated imidazolium precatalyst was...
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2014
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142640/ https://ncbi.nlm.nih.gov/pubmed/24895280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201403446 |
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