Anakinra as an interleukin 1 receptor antagonist, complicated genetics and molecular impacts- from the point of view of mouse genomics

IL-1 receptor antagonist (IL-1rn) is a protein that binds to IL-1 receptors (IL-1r1) and inhibits the binding of IL-1α and IL-1β. In recent years, IL-1rn has been implicated to be associated with many human health problems. The effects of treatment of several inflammatory disorders with anakinra, wh...

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Bibliografiske detaljer
Main Authors: Cao, Yanhong, Jiao, Yan, Wang, Lishi, Huang, Yue, Postlethwaite, Arnold, Stuart, John, Kang, Andy, Williams, Robert W., Gu, Weikuan
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142626/
https://ncbi.nlm.nih.gov/pubmed/22425556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2012.02.014
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