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The XMAP215 family drives microtubule polymerization using a structurally diverse TOG array
XMAP215 family members are potent microtubule (MT) polymerases, with mutants displaying reduced MT growth rates and aberrant spindle morphologies. XMAP215 proteins contain arrayed tumor overexpressed gene (TOG) domains that bind tubulin. Whether these TOG domains are architecturally equivalent is un...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142611/ https://ncbi.nlm.nih.gov/pubmed/24966168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-08-0501 |
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