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MCAK-Independent Functions of ch-Tog/XMAP215 in Microtubule Plus-End Dynamics
The formation of a functional bipolar mitotic spindle is essential for genetic integrity. In human cells, the microtubule polymerase XMAP215/ch-Tog ensures spindle bipolarity by counteracting the activity of the microtubule-depolymerizing kinesin XKCM1/MCAK. Their antagonistic effects on microtubule...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593372/ https://ncbi.nlm.nih.gov/pubmed/18809577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01040-08 |
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