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CEBPA exerts a specific and biologically important proapoptotic role in pancreatic β cells through its downstream network targets
Transcription factor CEBPA has been widely studied for its involvement in hematopoietic cell differentiation and causal role in hematological malignancies. We demonstrate here that it also performs a causal role in cytokine-induced apoptosis of pancreas β cells. Treatment of two mouse pancreatic α a...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142607/ https://ncbi.nlm.nih.gov/pubmed/24943845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-02-0703 |
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