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miR-296-3p, miR-298-5p and their downstream networks are causally involved in the higher resistance of mammalian pancreatic α cells to cytokine-induced apoptosis as compared to β cells

BACKGROUND: The molecular bases of mammalian pancreatic α cells higher resistance than β to proinflammatory cytokines are very poorly defined. MicroRNAs are master regulators of cell networks, but only scanty data are available on their transcriptome in these cells and its alterations in diabetes me...

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Main Authors: Barbagallo, Davide, Piro, Salvatore, Condorelli, Angelo G, Mascali, Loriana G, Urbano, Francesca, Parrinello, Nunziatina, Monello, Adelina, Statello, Luisa, Ragusa, Marco, Rabuazzo, Agata M, Di Pietro, Cinzia, Purrello, Francesco, Purrello, Michele
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571888/
https://ncbi.nlm.nih.gov/pubmed/23360399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-62
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