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The genetic basis of Lynch syndrome and its implications for clinical practice and risk management

Lynch syndrome is the most common cause of hereditary colon cancer, and accounts for as much as 3% of all colon and endometrial cancers. The identification and management of individuals with Lynch syndrome have evolved over the past 20 years, yet the syndrome remains vastly underdiagnosed. It is imp...

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Bibliographic Details
Main Authors: Cohen, Stephanie A, Leininger, Anna
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142571/
https://ncbi.nlm.nih.gov/pubmed/25161364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S51483
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