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The genetic basis of familial adenomatous polyposis and its implications for clinical practice and risk management

Familial adenomatous polyposis (FAP) is an inherited disorder that represents the most common gastrointestinal polyposis syndrome. Germline mutations in the APC gene were initially identified as responsible for FAP, and later, several studies have also implicated the MUTYH gene as responsible for th...

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Foilsithe in:Appl Clin Genet
Main Authors: Leoz, Maria Liz, Carballal, Sabela, Moreira, Leticia, Ocaña, Teresa, Balaguer, Francesc
Formáid: Artigo
Teanga:Inglês
Foilsithe: Dove Medical Press 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404874/
https://ncbi.nlm.nih.gov/pubmed/25931827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S51484
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