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The genetic basis of familial adenomatous polyposis and its implications for clinical practice and risk management

Familial adenomatous polyposis (FAP) is an inherited disorder that represents the most common gastrointestinal polyposis syndrome. Germline mutations in the APC gene were initially identified as responsible for FAP, and later, several studies have also implicated the MUTYH gene as responsible for th...

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Dettagli Bibliografici
Pubblicato in:Appl Clin Genet
Autori principali: Leoz, Maria Liz, Carballal, Sabela, Moreira, Leticia, Ocaña, Teresa, Balaguer, Francesc
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404874/
https://ncbi.nlm.nih.gov/pubmed/25931827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S51484
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