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Potential opportunities and perils of imperfect dengue vaccines

Dengue vaccine development efforts have focused on the development of tetravalent vaccines. However, a recent Phase IIb trial of a tetravalent vaccine indicates a protective effect against only 3 of the 4 serotypes. While vaccines effective against a subset of serotypes may reduce morbidity and mort...

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Autors principals: Rodriguez-Barraquer, Isabel, Mier-y-Teran-Romero, Luis, Schwartz, Ira B., Burke, Donald S., Cummings, Derek A.T.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142437/
https://ncbi.nlm.nih.gov/pubmed/24269318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.11.020
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