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Benefits and risks of the Sanofi-Pasteur dengue vaccine: Modeling optimal deployment

The first approved dengue vaccine has now been licensed in six countries. We propose that this live attenuated vaccine acts like a silent natural infection in priming or boosting host immunity. A transmission dynamic model incorporating this hypothesis fits recent clinical trial data well and predic...

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Publicado en:Science
Autores principales: Ferguson, Neil M., Rodríguez-Barraquer, Isabel, Dorigatti, Ilaria, Mier-y-Teran-Romero, Luis, Laydon, Daniel J., Cummings, Derek A. T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268127/
https://ncbi.nlm.nih.gov/pubmed/27701113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf9590
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